GlobalMD is going to organize the first NIH's Principles of Clinical Pharmacology Training Course in China in June 8-12^th, 2009

The NIH designed course on “Principles of Clinical Pharmacology” consists of a lecture series covering the fundamentals of clinical pharmacology as a translational scientific discipline focused on rational drug development and utilization in therapeutics.  Clinical Center

The recommended textbook is Principles of Clinical Pharmacology, Second Edition (2007) edited by Arthur J. Atkinson, Jr., et al. and published by Academic Press/Elsevier. The course is taught by faculty members from the National Institutes of Health (NIH) and guest faculty from the Food and Drug Administration (FDA), the pharmaceutical industry, and several academic institutions from across the United States.

The material included in this course complements the Clinical’s course on “Introduction to the Principles and Practice of Clinical Research.” Center

Because most medical schools lack a formal course in clinical pharmacology, and physicians, pharmacists, and other scientists in training may not have access to a formal educational curriculum in this discipline, this course was designed to assist interested individuals who are preparing to take the certifying examinations of the American Board of Clinical Pharmacology. Likewise, this course is offered to meet the needs of researchers with an interest in the clinical pharmacologic aspects of contemporary drug development and utilization.

Previous Course Video can be viewed from the following links:

Introducation to Course of PCP

MODULE 1: PHARMACOINETTICS

Clinical Pharmacokinetics

Chemical Assay of Drugs and Drug Metabolites

Compartmental analysis of drug distribution

Drug absorption and bioavailability

Use of positron emission tomography (PET) in Pharmacokinetics

PET lecture (1)

PET lecture (2)

Effects of renal disease on pharmacokinetics

Special lecture: Pharmacokinetics in patients requiring renal replacement therapy

Noncompartmental va. compartmental approaches to PK analysis

Effects of liver disease on pharmacokinetics

MODULE 2: DRUG METABOLISM AND TRANSPORT

Pathways of drug metabolism

Pharmacogenomics

Biochemical mechanisms of drug toxicity

Special lecture: P-glycoprotein and drug transport

MODULE 3: ASSESSMENT OF DRUG EFFECTS

Dose response and concentration response analysis

Disease progression models and clinical trial simulation

MODULE 4: OPTIMIZING AND EVALUATING PATIENT THERAPY

Drug therapy in pregnant and nursing women

Developmental and pediatric pharmacology

Drug therapy in the elderly

Quality assessment of drug therapy

Clinical analysis of adverse drug reactions

MODULE 5: DRUG DISCOVERY AND DEVELOPMENT

Drug discovery

Pre-clinical drug development

Animal scale up and Phase I studies( by Dr Dedrick)

Animal scale up and Phase I studies ( by Dr Collin)

Pharmacokinetics of biotechnology products and large molecules

Role of the FDA in guiding drug development